Early Career Researchers

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Open Positions

Currently there are no positions available.

If you are interested in the projects of our CRC you can look for open position here.

Open Positions

Project Area A

Biology and Molecular Oncology

© CRC1430

Doctoral Researcher Christian Cozma

Investigation of molecular mechanisms that regulate the organization and dynamics of microtubules during cell division

Project A01
© CRC1430

Doctoral Researcher Richard Pleuger

Recruitment of mitotic regulators to the budding yeast kinetochore

Project A01
© CRC1430

Doctoral Researcher Jason Mak

Investigation of force sensing mechanism at the kinetochore-mirotubule interface

Project A02
© CRC1430

Doctoral Researcher Sandra Koska

Cellular functions of p97 and its SEP-domain adapters

Project A03
© CRC1430

Doctoral Researcher Alexander Kroening

Biochemical and functional dissection of p97-cofactor interactions

Project A03
© CRC1430

Doctoral Researcher Daniella Munro

The role of VCP/p97 in cellular stress responses and checkpoint signalling

Project A03
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Postdoc Maike Reinders (former Giesing)

A rapid degradation approach for VCP/p97 cofactor proteins and its application in analyzing Ataxin-3 function in lysophagy

Project A03
© CRC1430

Doctoral Researcher Cole Bourque

High-resolution structural analysis and reconstruction of the Dam1 complex and associated proteins

Project A04
© CRC1430

Doctoral Researcher Athina Drakonaki

Structural analysis of p97- PLAA using SPA cryo-EM

Project A04
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https://pixabay.com/de/illustrations/silhouette-person-kopf-feedback-1825507/

Doctoral Researcher Eda Şamiloğlu Tengirşek

Structural Biology in Cellular Compartments: Peroxisomes

Project A04
© CRC1430

Doctoral Researcher Eman Zaffar

Role of MTBP-CDK8 in regulating replication origin firing in higher eukaryotes

Project A05
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© CRC1430

Doctoral Researcher Michelle Koci

Implication of deregulated proteostasis in melanoma

Project A06
© CRC1430

Doctoral Researcher Bastian Möllers

Biochemical and Cell Biological Characterization of the HTRA1-p97 Protein Complex

Project A06
© CRC1430

Doctoral Researcher Hai Trinh

Implication of deregulated proteostasis in melanoma

Project A06
© CRC1430

Doctoral Researcher Lana Buzuk

How are Golgi Quality Control Substrates Targeted to the Lysosome for Degradation?

Project A07
© CRC1430

Doctoral Researcher Melisa Kadic

Stress-induced ubiquitination at the Golgi Apparatus

Project A07
© CRC1430

Doctoral Researcher Gina Simon

The role of FAM129A in Golgi stress and cell state transitions

Project A07
© CRC1430

Doctoral Researcher Katarina Blazevic

Investigating the subcellular Rho activity dynamics during cell cycle transitions and the control by distinct GEF families

Project A08
© CRC1430

Postdoc Kristina Mrug

Regulation of the pulsatory contraction signal network dynamics during cell division

Project A08
© CRC1430

Doctoral Researcher Nicole Schrenke

The switch of Rho contractility signaling in drug resistant melanoma

Project A08
© CRC1430

Doctoral Researcher Alexandra Hommel

Rapid degradation of KDM5B induces a cell-stress-related vulnerability in melanoma cells

Project A11
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Doctoral Researcher Egor Pavlenko

Functional characterization of PRC2 dimerization on chromatin and structural analyses of mitochondrial complex formation of Apoptosis-inducing factor 1

Project A12
© CRC1430

Doctoral Researcher Till Rüngeler

Structure and regulatory interactions of human histone demethylase KDM5B

Project A12
© CRC 1430

Clinician Scientist Johanna A. Seier

Epigenetische Kontrolle des Interferon Signalweges und Th1-Typ Chemokinexpression im MYCN-amplifizierten Neuroblastom

Project A13
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© CRC1430

Doctoral Researcher Shannon Conroy

Compound based approach inhibiting the metastatic cell state transition in pancreatic cancer

 

Project A14
https://pixabay.com/de/illustrations/silhouette-person-kopf-feedback-1825507/
https://pixabay.com/de/illustrations/silhouette-person-kopf-feedback-1825507/

Doctoral Researcher Sebastian Urban

Unraveling the molecular function of USP7 in PDAC: Impact on Metabolism and EMT Dynamics

Project A14

Project Area B

Chemical Biology

© CRC1430

Doctoral Researcher Niko Molke

Entwicklung neuer PROTAC-Systeme

Project B01
© CRC1430

Doctoral Researcher Lukas Schrapp

Investigations on modulation of cancer cell migration via small molecules

Project B01
© CRC1430

PhD Doctoral Researcher Nikolas Klink

Synthesis and Evaluation of PROTACs for Degradation of Deubiquitinases

Project B02
© CRC 1430

PhD Doctoral Researcher Martin Schwalm

Hijacking the ubiquitin and autophagy system for the development of chemical degraders

Project B03
https://pixabay.com/de/illustrations/silhouette-person-kopf-feedback-1825507/

Doctoral Researcher Janik Weckesser

Development of heterobifunctional molecules using new E3 ligase ligands

Project B03
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© CRC 1430

Doctoral Researcher Julio Cesar Vieyto Nuñez

Computational studies of enzymes and supramolecular ligands

Project B04

Project Area Z

Central Services

"© C.Schubert/ZMB
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Alumni

© CRC1430

Postdoc Alexander Dudziak

Biochemical and genetic analysis of Dam1c ring assembly at the budding yeast kinetochore

Project A01
https://pixabay.com/de/illustrations/silhouette-person-kopf-feedback-1825507/

PhD student Pinki Gahlot

Lysosomal damage sensing and lysophagy initiation by SPG20-ITCH

Project A03
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Alumni Daniel Isaza

Elucidating the role of PLAA as a cofactor of p97 in lysophagy

Project A03
© CRC1430

PhD student Helen Müschenborn

Cellular functions of p97 adapters

Project A03
https://pixabay.com/de/illustrations/silhouette-person-kopf-feedback-1825507/

Postdoc Giulia Rota

Regulation of protein ubiquitination during lysophagy

Project A03
© CRC1430

Alumni Milena Parlak

TopBP1 loads GINS onto the Metazoan Mcm2-7 Helicase during Replication Origin Firing

Project A05
© CRC 1430

Alumni Bilal Tetik

Bipartite GINS binding mode of TopBP1 to activate the metazoan Mcm2-7 replicative helicase

Project A05
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Alumni Birte Hagemeier

Mechanistic insights into the interactions of HTRA1 with pathological Tau species

Project A06
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Alumni Savina Abraham-Pol

Stress-induced Golgi remodelling revealed by chemical biology stress models

Project A07
https://pixabay.com/de/illustrations/silhouette-person-kopf-feedback-1825507/
https://pixabay.com/de/illustrations/silhouette-person-kopf-feedback-1825507/
https://pixabay.com/de/illustrations/silhouette-person-kopf-feedback-1825507/
https://pixabay.com/de/illustrations/silhouette-person-kopf-feedback-1825507/

Alumni Beatrice Thier

Treatment-induced sculpting of melanoma phenotype and immunogenicity – Impact on resistance to CD8 T cells

Project A13
https://pixabay.com/de/illustrations/silhouette-person-kopf-feedback-1825507/

Alumni Mirko Schmidt

Design, Synthesis and Biological Evaluation of Tool Compounds for the Cellular Investigation of Deubiquitinases

Project B02
https://pixabay.com/de/illustrations/silhouette-person-kopf-feedback-1825507/
https://pixabay.com/de/illustrations/silhouette-person-kopf-feedback-1825507/

PhD student Stefan Kleine

Synthese und biologische Validierung hetero-bifunktionaler Moleküle zum gerichteten Proteinabbau in Bakterien

Project Z03
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PhD student David Podlesainski

Elucidation of the mode-of-action of the anti-tubercular Callyaerins

Project Z03
https://pixabay.com/de/illustrations/silhouette-person-kopf-feedback-1825507/

Alumni Maria Tsipa

Development of BacPROTACs based on ClpC binders

Project Z03
https://pixabay.com/de/illustrations/silhouette-person-kopf-feedback-1825507/